ABSTRACT
The Mondo Disease Ontology (Mondo) represents cross-species diseases, which integrates several source disease terminologies to represent cross-species diseases, and provides precise semantic mappings to the original sources. Mondo spans both rare and 'common' diseases, as well as monogenic, acquired, neoplasms, infectious diseases, and more. Mondo is a community resource and is continuously updated and iteratively curated. Recent efforts sought to improve the representation of viral infectious diseases in Mondo, to properly represent primary infections, diseases caused by reactivation of a latent virus, such as shingles and diseases caused by aftereffects of a primary infection such as long COVID-19. This included the addition of new classes and new relations (object properties), and the creation of new design patterns. © 2021 Copyright for this paper by its authors.